Recombinant Mouse Cuteaneous T-cell Attracting Chemokine/CCL27 (Mouse CTACK/CCL27)_C230533

Description

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T cells and directs them into the skin. CTACK
contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant Murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.

 

Product Properties

Synonyms
CCL27
Accession
Q9Z1X0
GeneID
20301

Source
E.coli-derived Mouse CCL27 protein,Leu26-Asn120.

Molecular Weight
Approximately 10.9 kDa
AA Sequence

LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS
LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity
> 98% by SDS-PAGE and HPLC analyses.
Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis
bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.

Endotoxin
<1 EU/μg of protein as determined by LAL method.

Formulation
Lyophilized from a 0.2 µm filtered concentrated solution in 2 × PBS, pH 7.4, with 5% trehalose.

Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further
dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.

Recombinant Mouse Cuteaneous T-cell Attracting Chemokine/CCL27 (Mouse CTACK/CCL27)_C230533

Product form

SKU: C230533E

$74.00

    • Shipped today? Order within: Jan 17, 2025 17:00:00 -0500
    • Tell a unique detail about this product

    Description

    CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T cells and directs them into the skin. CTACK
    contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant Murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.

     

    Product Properties

    Synonyms
    CCL27
    Accession
    Q9Z1X0
    GeneID
    20301

    Source
    E.coli-derived Mouse CCL27 protein,Leu26-Asn120.

    Molecular Weight
    Approximately 10.9 kDa
    AA Sequence

    LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS
    LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN
    Tag
    None
    Physical Appearance
    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity
    > 98% by SDS-PAGE and HPLC analyses.
    Biological Activity

    Fully biologically active when compared to standard. The biological activity determined by a chemotaxis
    bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.

    Endotoxin
    <1 EU/μg of protein as determined by LAL method.

    Formulation
    Lyophilized from a 0.2 µm filtered concentrated solution in 2 × PBS, pH 7.4, with 5% trehalose.

    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.
    Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further
    dilutions should be made in appropriate buffered solutions.

     

    Shipping and Storage

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

    1. Avoid repeated freeze-thaw cycles.
    2. For your safety and health, please wear lab coats and disposable gloves for operation.
    3. For research use only.

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