Recombinant Human PDGF-CC Protein,His Tag_C230224

Description

The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD.The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-α and PDGFR-β, and are potent mitogens for a variety of cell types. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules' epithelial cell development.

 

Product Properties

Synonyms

 

PDGFCC; PDGF-CC

 

Source

E.coli

Molecular Weight

Approximately 27 kDa, a disulfide-linked homodimer of two 117 amino acid, C-terminal polyhistidine tagged proteins.

AA Sequence

Accession :NP_057289 Val235-Gly345,  with an N-terminal Met and 6-His tag;

Biological Activity

Measured in a cell proliferation assay using NR6R3T3 mouse fibroblast cells. The ED50 for this effect is 70-350 ng/mL.

Purity

> 97% by SDS-PAGE.

Endotoxin

<0.1EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.2 µm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1 mg/mL. Further dilutions should be made in appropriately buffered solutions.

 

Shipping and Storage

The product should be stored at -25~-15℃ for 1 year from date of receipt.

1 month, 2 ~8 °C under sterile conditions after reconstitution.

3 months, -25~-15℃ under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1.Please operate with lab coats and disposable gloves,for your safety.

2.This product is for research use only.

Recombinant Human PDGF-CC Protein,His Tag_C230224

Product form

SKU: C230224E

$74.00

      • Tell a unique detail about this product

      Description

      The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD.The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-α and PDGFR-β, and are potent mitogens for a variety of cell types. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules' epithelial cell development.

       

      Product Properties

      Synonyms

       

      PDGFCC; PDGF-CC

       

      Source

      E.coli

      Molecular Weight

      Approximately 27 kDa, a disulfide-linked homodimer of two 117 amino acid, C-terminal polyhistidine tagged proteins.

      AA Sequence

      Accession :NP_057289 Val235-Gly345,  with an N-terminal Met and 6-His tag;

      Biological Activity

      Measured in a cell proliferation assay using NR6R3T3 mouse fibroblast cells. The ED50 for this effect is 70-350 ng/mL.

      Purity

      > 97% by SDS-PAGE.

      Endotoxin

      <0.1EU per 1μg of the protein by the LAL method.

      Formulation

      Lyophilized from 0.2 µm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA.

      Reconstitution

      We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 4 mM HCl to a concentration of 0.1 mg/mL. Further dilutions should be made in appropriately buffered solutions.

       

      Shipping and Storage

      The product should be stored at -25~-15℃ for 1 year from date of receipt.

      1 month, 2 ~8 °C under sterile conditions after reconstitution.

      3 months, -25~-15℃ under sterile conditions after reconstitution.

      Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

       

      Cautions

      1.Please operate with lab coats and disposable gloves,for your safety.

      2.This product is for research use only.

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