Recombinant Human Noggin Protein,His Tag _ C230462

Description

Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors.

 

Product Properties

 

Synonyms

NOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1

Uniprot No.
Q13253

Source

HEK293 cells -derived human Noggin protein, Gln28-Cys232, with a His tag at the C-terminal
Molecular Weight
The protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) .
Activity
Measured by its ability to bind BMP2 with Elisa method .
Optimal concentrations should be determined by each laboratory for each application
Purity
> 95% as determined by SDS-PAGE.
Endotoxin
<1.0 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.

 

Storage

 

The product should be stored at -85~-65℃ for 1 year from date of receipt.

 

Caution

 

1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.

Recombinant Human Noggin Protein,His Tag _ C230462

Product form

SKU: C230462E

$540.00

    • Shipped today? Order within: Feb 17, 2025 17:00:00 -0500
    • Tell a unique detail about this product

    Description

    Noggin is a bone morphogenetic protein (BMP) antagonist expressed in Spemann's organizer. It inhibits TGF-β family ligands and preventing them from binding to their corresponding receptors.

     

    Product Properties

     

    Synonyms

    NOG, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1

    Uniprot No.
    Q13253

    Source

    HEK293 cells -derived human Noggin protein, Gln28-Cys232, with a His tag at the C-terminal
    Molecular Weight
    The protein migrates as 30 KDa under reducing (R) condition (SDS-PAGE) .
    Activity
    Measured by its ability to bind BMP2 with Elisa method .
    Optimal concentrations should be determined by each laboratory for each application
    Purity
    > 95% as determined by SDS-PAGE.
    Endotoxin
    <1.0 EU per 1μg of the protein by the LAL method.
    Formulation
    Lyophilized from a 0.2 μm filtered solution in PBS.
    Reconstitution
    It is recommended that this vial be briefly centrifuged prior to opening to bring the contents
    to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.

     

    Storage

     

    The product should be stored at -85~-65℃ for 1 year from date of receipt.

     

    Caution

     

    1.Please operate with lab coats and disposable gloves,for your safety.
    2.This product is for research use only.

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