Description
Description
IL-10 is an anti-inflammatory cytokine. IL-10 is produced primarily by monocytes, but also secreted by T cells, macrophages, mast cells, and other cell lines. IL-10 can inhibit the secretion of cytokines such as IFN- γ, IL-2, IL-3, TNF and GM-CSF, which plays an important role in the fight against human transitional immunity. In addition, IL-10 may play a role in the clinical inhibition of organ transplantation rejection due to its immunosuppressive properties.
Product Properties
Synonyms
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CSIF;IL10
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Uniprot No.
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P05231
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Source
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Recombinant Human IL-10 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ser19-Asn178.
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Molecular Weight
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The protein has a predicted MW of 19.79 kDa.
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Purity
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> 95% as determined by SDS-PAGE.
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Endotoxin
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<0.1 EU per 1μg of the protein by the LAL method.
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Formulation
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Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
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Reconstitution
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Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL.
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Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt. 2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.