Recombinant Human Granulocyte Colony Stimulating Factor (Human G-CSF)_C230357

Description

G-CSF is a hematopoietic growth factor that stimulates the development of progenitor cells that transform to neutrophils and enhances the functional activity of mature terminal cells.G-CSF is produced in response to specific stimulation of a variety of cells, including macrophages, fibroblasts, endothelial cells, and the bone marrow stroma.G-CSF is used clinically to promote hematopoietic recovery after bone marrow transplantation.G-CSF is used clinically to promote hematopoietic recovery after bone marrow transplantation. This recombinant human G-CSF is supplied as a lyophilized powder with high activity, high purity, low endotoxin, and no redundant labeling.

 

Product Properties

Synonyms

G-CSF, CSF-3, MGI-1G, GM-CSF beta, MGC45931,Pluripoietin
Accession
P09919

Source

E.coli-derived Human G-CSF protein, Thr31-Pro204.

Molecular Weight

Approximately 18.9 kDa.

AA Sequence

TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 98 % by SDS-PAGE and HPLC analyses.

Biological Activity

The ED50 as determined by a cell proliferation assay using mouse NFS-60 cells is less than 0.05 ng/mL, corresponding to a specific activity of>2.0 x 107 lU/mg.Fully biologically active when compared to standard.

Endotoxin

< 0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 µm filtered solution in 10 mM Sodium Citrate, pH 4.0, 150 mM NaCl, 0.01% Tween-20.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only!

Recombinant Human Granulocyte Colony Stimulating Factor (Human G-CSF)_C230357

Product form

SKU: C230357E

$179.00

    • Shipped today? Order within: Feb 17, 2025 17:00:00 -0500
    • Tell a unique detail about this product

    Description

    G-CSF is a hematopoietic growth factor that stimulates the development of progenitor cells that transform to neutrophils and enhances the functional activity of mature terminal cells.G-CSF is produced in response to specific stimulation of a variety of cells, including macrophages, fibroblasts, endothelial cells, and the bone marrow stroma.G-CSF is used clinically to promote hematopoietic recovery after bone marrow transplantation.G-CSF is used clinically to promote hematopoietic recovery after bone marrow transplantation. This recombinant human G-CSF is supplied as a lyophilized powder with high activity, high purity, low endotoxin, and no redundant labeling.

     

    Product Properties

    Synonyms

    G-CSF, CSF-3, MGI-1G, GM-CSF beta, MGC45931,Pluripoietin
    Accession
    P09919

    Source

    E.coli-derived Human G-CSF protein, Thr31-Pro204.

    Molecular Weight

    Approximately 18.9 kDa.

    AA Sequence

    TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP

    Tag

    None

    Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

    Purity

    > 98 % by SDS-PAGE and HPLC analyses.

    Biological Activity

    The ED50 as determined by a cell proliferation assay using mouse NFS-60 cells is less than 0.05 ng/mL, corresponding to a specific activity of>2.0 x 107 lU/mg.Fully biologically active when compared to standard.

    Endotoxin

    < 0.1 EU per 1μg of the protein by the LAL method.

    Formulation

    Lyophilized from a 0.2 µm filtered solution in 10 mM Sodium Citrate, pH 4.0, 150 mM NaCl, 0.01% Tween-20.

     

    Shipping and Storage

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

    1. Avoid repeated freeze-thaw cycles.

    2. For your safety and health, please wear lab coats and disposable gloves for operation.

    3. For research use only!

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