Recombinant Human Interleukin-20 (Human IL-20)_ C230397

Description

IL-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. Human IL-20 is synthesized as a 176 amino acid (aa) precursor with a 24 aa signal sequence and a 152 aa mature segment. IL-20 production has been found in skin, trachea, and other tissues. In particular, it is produced by activated keratinocytes and monocytes. It has been shown that IL-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, it is reported to induce the proliferation of multipotential hematopoietic progenitor cells, direct the differentiation and expansion of keratinocytes, and promote the release of proinflammatory mediators in keratinocytes and other IL-20 receptor expressing cells.

 

Product Properties

 

Synonyms

Cytokine Zcyto10

Source

E.coli-derived Human IL-20, Leu25-Glu176, with an N-terminal Met.

AA sequence

MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE 

Endotoxin

< 1.0 EU per μg by the LAL method.

Purity

> 95% by SDS-PAGE and HPLC analyses.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2, with trehalose.

Applications

ELISA, Kinetics (BLI), Kinetics (SPR), Immunization

Dilution

Dilute in sterile distilled water or aqueous buffer containing 0.1% BSA.

 

Storage

 

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

 

1. Please operate with lab coats and disposable gloves,for your safety.       

2. This product is for research use only.  

Recombinant Human Interleukin-20 (Human IL-20)_ C230397

Product form

SKU: C230397E

$179.00

    • Shipped today? Order within: Mar 26, 2025 17:00:00 -0400
    • Tell a unique detail about this product

    Description

    IL-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. Human IL-20 is synthesized as a 176 amino acid (aa) precursor with a 24 aa signal sequence and a 152 aa mature segment. IL-20 production has been found in skin, trachea, and other tissues. In particular, it is produced by activated keratinocytes and monocytes. It has been shown that IL-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, it is reported to induce the proliferation of multipotential hematopoietic progenitor cells, direct the differentiation and expansion of keratinocytes, and promote the release of proinflammatory mediators in keratinocytes and other IL-20 receptor expressing cells.

     

    Product Properties

     

    Synonyms

    Cytokine Zcyto10

    Source

    E.coli-derived Human IL-20, Leu25-Glu176, with an N-terminal Met.

    AA sequence

    MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE 

    Endotoxin

    < 1.0 EU per μg by the LAL method.

    Purity

    > 95% by SDS-PAGE and HPLC analyses.

    Formulation

    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2, with trehalose.

    Applications

    ELISA, Kinetics (BLI), Kinetics (SPR), Immunization

    Dilution

    Dilute in sterile distilled water or aqueous buffer containing 0.1% BSA.

     

    Storage

     

    The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.

    Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

     

    Cautions

     

    1. Please operate with lab coats and disposable gloves,for your safety.       

    2. This product is for research use only.  

    © 2025 Arcegen, Powered by Shopify

    • American Express
    • Apple Pay
    • Diners Club
    • Discover
    • Google Pay
    • Mastercard
    • Shop Pay
    • Visa

    Login

    Forgot your password?

    Don't have an account yet?
    Create account