Fibroblast growth factor-17( FGF17) is one of the fibroblast growth factor( FGF) family members and it makes up FGF8 subfamily along with FGF8 and FGF18. Mature human FGF- 17 shares 99% aa identity with mouse, rat, porcine and canine FGF- 17. The FGF
domain of FGF- 17 shares the most aa identity with FGF- 8 (~75%) and FGF- 18 (~64%). Among different members of the FGF family, FGF17 and FGF8 share high sequence homology and have similar patterns of expression during embryogenesis. FGF- 17 is
also expressed in adult bovine ovarian follicles and the human prostate, and its expression is increased by both benign hypertrophy and cancer of the prostate.
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