Recombinant Human Fibroblast Growth Factor 17 (Human FGF-17)_C230342

Description

Fibroblast growth factor-17( FGF17) is one of the fibroblast growth factor( FGF) family members and it makes up FGF8 subfamily along with FGF8 and FGF18. Mature human FGF- 17 shares 99% aa identity with mouse, rat, porcine and canine FGF- 17. The FGF
domain of FGF- 17 shares the most aa identity with FGF- 8 (~75%) and FGF- 18 (~64%). Among different members of the FGF family, FGF17 and FGF8 share high sequence homology and have similar patterns of expression during embryogenesis. FGF- 17 is
also expressed in adult bovine ovarian follicles and the human prostate, and its expression is increased by both benign hypertrophy and cancer of the prostate.

 

Product Properties

Synonyms

FGF17, FGF-17, fibroblast growth factor 17
Accession
O60258
GeneID
8822
Source
E.coli-derived human FGF-17 protein, Thr23-Thr216, with an N-terminal Met.
Molecular Weight
Approximately 22.6 kDa
AA Sequence
MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
>95% by SDS-PAGE and HPLC analyses.
Biological Activity
The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0 × 10 5 IU/mg. Fully biologically active when compared to standard.
Endotoxin
< 0.1 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Reconstitution
Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!

Recombinant Human Fibroblast Growth Factor 17 (Human FGF-17)_C230342

Product form

SKU: C230342E

$74.00

      • Tell a unique detail about this product

      Description

      Fibroblast growth factor-17( FGF17) is one of the fibroblast growth factor( FGF) family members and it makes up FGF8 subfamily along with FGF8 and FGF18. Mature human FGF- 17 shares 99% aa identity with mouse, rat, porcine and canine FGF- 17. The FGF
      domain of FGF- 17 shares the most aa identity with FGF- 8 (~75%) and FGF- 18 (~64%). Among different members of the FGF family, FGF17 and FGF8 share high sequence homology and have similar patterns of expression during embryogenesis. FGF- 17 is
      also expressed in adult bovine ovarian follicles and the human prostate, and its expression is increased by both benign hypertrophy and cancer of the prostate.

       

      Product Properties

      Synonyms

      FGF17, FGF-17, fibroblast growth factor 17
      Accession
      O60258
      GeneID
      8822
      Source
      E.coli-derived human FGF-17 protein, Thr23-Thr216, with an N-terminal Met.
      Molecular Weight
      Approximately 22.6 kDa
      AA Sequence
      MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT
      Tag
      None
      Physical Appearance
      Sterile Filtered White lyophilized (freeze-dried) powder.
      Purity
      >95% by SDS-PAGE and HPLC analyses.
      Biological Activity
      The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0 × 10 5 IU/mg. Fully biologically active when compared to standard.
      Endotoxin
      < 0.1 EU per 1μg of the protein by the LAL method.
      Formulation
      Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
      Reconstitution
      Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

       

      Shipping and Storage

      The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
      Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

       

      Cautions

      1. Avoid repeated freeze-thaw cycles.
      2. For your safety and health, please wear lab coats and disposable gloves for operation.
      3. For research use only!

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