Recombinant Human FGF-19 Protein,Flag Tag_C230343

Description

FGF-19 is a member of the fibroblast growth factor (FGF) family. After being secreted from the intestine, FGF19 can enter the liver with the circulation and bind to FGFR4 in the liver to act. It has a hormone-like effect and plays an important role in metabolic regulation, such as regulating bile acid metabolism, regulating gallbladder filling, and
improving blood glucose. Notably, aberrant expression of FGF19/FGFR4 promotes HCC development and metastasis.

 

Product Properties

Synonyms

FGF19;Fibroblast growth factor 1
Uniprot No.
O95750
Source
Recombinant Human FGF-19 Protein is expressed from HEK293 Cells with Flag tag at the N-terminal. It contains Leu 25-Lys 216.
Molecular Weight
The protein has a predicted MW of 23.36 kDa. And it migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
> 95% as determined by SDS-PAGE.
Biological Activity
The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150 ng/mL.
Endotoxin
<0.1 EU per 1μg of the protein by the LAL method.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL.

 

Shipping and Storage

The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.

Recombinant Human FGF-19 Protein,Flag Tag_C230343

Product form

SKU: C230343S

$74.00

      • Tell a unique detail about this product

      Description

      FGF-19 is a member of the fibroblast growth factor (FGF) family. After being secreted from the intestine, FGF19 can enter the liver with the circulation and bind to FGFR4 in the liver to act. It has a hormone-like effect and plays an important role in metabolic regulation, such as regulating bile acid metabolism, regulating gallbladder filling, and
      improving blood glucose. Notably, aberrant expression of FGF19/FGFR4 promotes HCC development and metastasis.

       

      Product Properties

      Synonyms

      FGF19;Fibroblast growth factor 1
      Uniprot No.
      O95750
      Source
      Recombinant Human FGF-19 Protein is expressed from HEK293 Cells with Flag tag at the N-terminal. It contains Leu 25-Lys 216.
      Molecular Weight
      The protein has a predicted MW of 23.36 kDa. And it migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
      Purity
      > 95% as determined by SDS-PAGE.
      Biological Activity
      The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150 ng/mL.
      Endotoxin
      <0.1 EU per 1μg of the protein by the LAL method.
      Formulation
      Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
      Reconstitution
      Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL.

       

      Shipping and Storage

      The product should be stored at -25~-15℃ for 1 year from date of receipt.
      2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
      3 months, -25~-15℃ under sterile conditions after reconstitution.
      Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

       

      Cautions

      1.Please operate with lab coats and disposable gloves,for your safety.
      2.This product is for research use only.

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